Tag Archives: Prolozone

Interstitial Cystitis vs. UTI: How Platelet-Rich Plasma (PRP) and Ozone Therapy Offer New Hope for Lasting Relief

By asmithers | Published June 17, 2026

If you have been told you have a UTI but antibiotics are not working, you may actually be dealing with Interstitial cystitis (IC) rather than a standard UTI. The two conditions share nearly identical symptoms, yet they demand fundamentally different treatment approaches. For the millions of Americans trapped in this diagnostic gray zone, the frustration is real: negative urine Continue reading

Posted in What We Treat | Also tagged Bacterial Vaginosis, Celebrities with Interstitial cystitis, Chinese Medicine Sarasota, Chronic UTI, Interstitial Cystitis, Prolotherapy Bradenton, Prolotherapy Sarasota, Vaginal Candidiasis Comments Off

Prolotherapy vs. PRP vs. Prolozone Therapy | Integral Medicine Sarasota

By asmithers | Published June 11, 2026

If you’ve been living with chronic joint pain, a torn ligament, or an injury that won’t heal — and you’re not ready to accept surgery as your only option — you’ve probably come across the terms Prolotherapy, PRP, and Prolozone.

They all fall under the umbrella of regenerative injection therapy. They all aim to do the same thing: trigger Continue reading

Posted in Uncategorized | Also tagged avoid surgery, Bradenton, chronic pain, integrative medicine, joint pain, Prolotherapy, PRP, regenerative medicine, Sarasota Comments Off

The clinical efficacy of ozone combined with steroid in the treatment of discogenic low back pain: a randomized, double-blinded clinical study

By asmithers | Published July 7, 2025

Xiao-hui Yang 1, Xiao-hui Liu 1, Yun-gai Ma 1, Jia-xing Fan 1, Xiao-long Ma 1, Guan-ying Zhuang 1, Zhan-min Yang 1,* Author information Article notes Copyright and License information PMCID: PMC10448056 PMID: 37638178 Abstract Objective

This randomized double-blinded clinical study is to Continue reading

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Low-Carbohydrate Diet Superior to Antipsychotic Medications

By asmithers | Published October 6, 2017

A Cutting-Edge Conference

This summer, I was fortunate to participate in the groundbreakingInternational Society for Nutritional Psychiatry Research(ISNPR) conference held in Bethesda, Maryland. The meeting was truly inspiring and exciting to those of us who believe that nutritional approaches are the way forward in the treatment of mental healthdisorders. While the Continue reading

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Probiotic Reduces Depression and Alters Brain Activity in IBS

By asmithers | Published July 3, 2017

Gastroenterology

TAKE-HOME MESSAGE The effect of the probiotic Bifidobacterium longum NCC3001 on psychiatric symptoms was evaluated in 44 individuals with IBS and mild to moderate anxiety and depression in this randomized placebo-controlled trial. Compared with the placebo group, significantly more patients in the probiotic group had reduced depression scores, but not anxiety scores, at week 6. The probiotic group also had Continue reading

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Integral Medicine | Alexander Smithers M.D., A.P.

1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336
1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336
Testimonials

Doctor Alex has been treating me for severe gut issues. I was tired of going to doctors that didn’t listen to me and would just prescribe a pill not ever trying to get to the real issues I was having. Dr. Alex has listened and treated me holistically and I am feeling great!! Thank you for everything Dr. Alex.
In Oct of 2013 I was diagnosed with stage 4 Cholangiocarcinoma Malignant Neoplasm Cancer of the Bile Ducts of the Liver. In addition I had a tumor on the left lobe of the liver that ruptured and allowed cancer cells to escape and cake on the majority of my abdominal area. The issues, pain and effects are too numerous to mention. After 9 months of Chemo Therapy Treatments I was left with major issues with neuropathy in both my feet... Read more »
Dear Dr. Smithers,

I just wanted to thank you for treating my trigeminal neuralgia pain.

In May of 2012 I hit my head on a concrete ledge resulting in severe head trauma with unusual and very painful symptoms that followed—throbbing, knife stabbing, severe tension in and around my head, constant clicking noise, and my soft palate in continual motion. I was first diagnosed with TMJ for which I was given an appliance to align my jaw. Which did not take away the severe pain... Read more »
Testimonials

I was told i needed surgery and that i should file for social security disability… I thought my life was over . Thanks to Dr Smithers i didn’t have to do either.. I will be eternally grateful… I’m back at work and looking forward to a bright future..
I had my second appointment with Dr. Alex Smithers today. I was treated for painful arthritic hip, back, and neck. After treatments I felt immediate results. I was able to go shopping with my daughter with no pain which wouldn’t have been possible before without considerable pain. I am very thankful to my daughter who found Dr. Alex and this office. I am also very thankful to Dr. Alex. I have flown twice from Pa. To see him and will... Read more »
I couldn’t be happier with the treatment I received from Dr Smithers. I had been having knee pain for several months, making it difficult to walk for an extended period of time. I finally decided to have Dr Smithers look at it, and he decided to do prolotherapy. After a few treatments, the pain was completely gone. I’m thrilled to have found this clinic! And I highly recommend Dr Smithers!
Thank you Dr. Alex Smithers! After dealing with lower back pain from an injury 30 years ago, I feel that after several injections, I am pain and worry free and can finally let this go.
I was back today for a torn knee ligament and the first ozone injection, and am confident this will be healed also.
Alex is unlike others in the medical field. He has a calm professional manner and very patient in listening and explaining... Read more »
Dear Dr. Smithers,

This letter is to thank you for your caring, skills and services. Having Reflex Sympathetic Dystrophy for over five years was pure misery. I visited over 30 doctors in over a dozen states. I scoured the computer for the best of the best, which included university professors and authors on Prolotherapy and Orthopedics. Four of those even taught Prolotherapy while others focused on Stem Cells. I even received advice on the countries leading scientist on cartilage.... Read more »
Dr. Smithers is a wonderful doctor with a wealth of knowledge in a variety of areas. I had been suffering with a parasitic infection for a year and a half that left me with many gastrointestinal symptoms. He told me exactly how to treat it and heal my gut. I am forever in debt to him for fixing me! He is bright, friendly, kind, welcoming, & has great bedside manner. I would highly recommend seeing him for any issue.
... Read more »