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The clinical efficacy of ozone combined with steroid in the treatment of discogenic low back pain: a randomized, double-blinded clinical study

By asmithers | Published July 7, 2025

Xiao-hui Yang 1, Xiao-hui Liu 1, Yun-gai Ma 1, Jia-xing Fan 1, Xiao-long Ma 1, Guan-ying Zhuang 1, Zhan-min Yang 1,* Author information Article notes Copyright and License information PMCID: PMC10448056 PMID: 37638178 Abstract Objective

This randomized double-blinded clinical study is to Continue reading

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Integral Medicine | Alexander Smithers M.D., A.P.

1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336
1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336
Testimonials

I couldn’t be happier with the treatment I received from Dr Smithers. I had been having knee pain for several months, making it difficult to walk for an extended period of time. I finally decided to have Dr Smithers look at it, and he decided to do prolotherapy. After a few treatments, the pain was completely gone. I’m thrilled to have found this clinic! And I highly recommend Dr Smithers!
I was told i needed surgery and that i should file for social security disability… I thought my life was over . Thanks to Dr Smithers i didn’t have to do either.. I will be eternally grateful… I’m back at work and looking forward to a bright future..
Dear Dr. Smithers,

This letter is to thank you for your caring, skills and services. Having Reflex Sympathetic Dystrophy for over five years was pure misery. I visited over 30 doctors in over a dozen states. I scoured the computer for the best of the best, which included university professors and authors on Prolotherapy and Orthopedics. Four of those even taught Prolotherapy while others focused on Stem Cells. I even received advice on the countries leading scientist on cartilage.... Read more »
Testimonials

I was told i needed surgery and that i should file for social security disability… I thought my life was over . Thanks to Dr Smithers i didn’t have to do either.. I will be eternally grateful… I’m back at work and looking forward to a bright future..
I couldn’t be happier with the treatment I received from Dr Smithers. I had been having knee pain for several months, making it difficult to walk for an extended period of time. I finally decided to have Dr Smithers look at it, and he decided to do prolotherapy. After a few treatments, the pain was completely gone. I’m thrilled to have found this clinic! And I highly recommend Dr Smithers!
I had been suffering from chronic neck and shoulder pain for almost 2 decades. I tried chiropractic and acupuncture, which didn’t do anything for my pain. Using essential oils and CBD would help, but that was a temporary fix. Through an online documentary, I found this clinic in Sarasota. Meeting Dr. Smithers was the best thing that ever happened to me. He’s not just a very competent doctor, he’s also very compassionate and patient. He’s extremely knowledgeable and well read,... Read more »
Dr Smithers is so acute and atuned to what others miss. I had been suffering with abdominal issues for over 20 years getting no help from traditional medicine. He found and correctly treated the issue. Words cannot describe the quality of life that has been restored to me. He’s very caring and takes the time to listen.
Dear Dr. Smithers,

I just wanted to thank you for treating my trigeminal neuralgia pain.

In May of 2012 I hit my head on a concrete ledge resulting in severe head trauma with unusual and very painful symptoms that followed—throbbing, knife stabbing, severe tension in and around my head, constant clicking noise, and my soft palate in continual motion. I was first diagnosed with TMJ for which I was given an appliance to align my jaw. Which did not take away the severe pain... Read more »
Doctor Alex has been treating me for severe gut issues. I was tired of going to doctors that didn’t listen to me and would just prescribe a pill not ever trying to get to the real issues I was having. Dr. Alex has listened and treated me holistically and I am feeling great!! Thank you for everything Dr. Alex.