Tag Archives: natural pain relief

FDA Advisory Committee to Review Cell Therapy for Duchenne Muscular Dystrophy

By asmithers | Published July 26, 2026

The FDA’s Cellular, Tissue, and Gene Therapies Advisory Committee meets July 29 to review Capricor Therapeutics’ deramiocel, an investigational allogeneic cell therapy for Duchenne muscular dystrophy. The meeting comes ahead of an August 22 target decision date and follows a prior rejection of the company’s first application.

Table of Contents What’s Happening How Deramiocel Works What the Data Show Why Continue reading

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FDA Approves Tregzi, First Regulatory T-Cell Therapy to Reduce Chronic GVHD

By asmithers | Published July 18, 2026

The FDA has approved Tregzi, a precision-engineered cell therapy from Orca Bio, as the first regulatory T-cell (Treg) based treatment for adults undergoing allogeneic stem cell transplants for blood cancers. Trial data showed it more than doubled one-year survival free of chronic graft-versus-host disease compared with standard transplants.

Table of Contents What Happened How Tregzi Works What the Data Show Continue reading

FDA Grants RMAT Status to Allocetra, a Cell Therapy for Knee Osteoarthritis

By asmithers | Published July 14, 2026

FDA Grants RMAT Status to Allocetra, a Cell Therapy for Knee Osteoarthritis

The FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation to Allocetra, an investigational cell therapy from Enlivex, for age-related symptomatic knee osteoarthritis in adults 64 and older. The designation is based on six-month data showing durable improvements in pain and function.

What Happened

The FDA has granted Continue reading

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Beyond Mold: A Complete Guide to Biotoxin Illness (CIRS) and How to Recover

By asmithers | Published July 13, 2026

If you have spent months or years cycling through specialists, collecting vague diagnoses like fibromyalgia or chronic fatigue syndrome, and feeling as though your body has become a stranger to you, you are not alone. You may be dealing with Biotoxin Illness/CIRS, a condition Continue reading

Medical Ozone Therapy for Chronic Fatigue: Energy Restoration

By asmithers | Published July 1, 2026

If you are living with chronic fatigue that rest cannot fix, you know the difference between being tired and being depleted. The exhaustion that defines myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is not the kind you can sleep off. It is a profound, cellular collapse that steals your ability Continue reading

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Integral Medicine | Alexander Smithers M.D., A.P.

1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336
1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336
Testimonials

Dear Dr. Smithers,

This letter is to thank you for your caring, skills and services. Having Reflex Sympathetic Dystrophy for over five years was pure misery. I visited over 30 doctors in over a dozen states. I scoured the computer for the best of the best, which included university professors and authors on Prolotherapy and Orthopedics. Four of those even taught Prolotherapy while others focused on Stem Cells. I even received advice on the countries leading scientist on cartilage.... Read more »
In Oct of 2013 I was diagnosed with stage 4 Cholangiocarcinoma Malignant Neoplasm Cancer of the Bile Ducts of the Liver. In addition I had a tumor on the left lobe of the liver that ruptured and allowed cancer cells to escape and cake on the majority of my abdominal area. The issues, pain and effects are too numerous to mention. After 9 months of Chemo Therapy Treatments I was left with major issues with neuropathy in both my feet... Read more »
Dr. Alex Smithers is outstanding…a talented Dr. Who is extremely passionate about healing as well as the skills involved in rejuvenative therapies. I go to him for ozone (prolozone) and dextrose (prolotherapy) injections. Have gone to him already at least 8 times. He uses ultrasound to diagnose and monitor and his injections really work. Best of all he’s a great guy and very easy to chat with.
Testimonials

Dr. Smithers has been taking care of my knees for a few years now. My experience with him has been consistently outstanding. His care has allowed me to avoid knee replacement surgery. There was a point when I had so much pain that I was not able to spend more than 15 minutes on my feet.. Because of his treatments and direction I have gotten my life back, including 20 mile bike rides and trips to the Disney parks with... Read more »
I couldn’t be happier with the treatment I received from Dr Smithers. I had been having knee pain for several months, making it difficult to walk for an extended period of time. I finally decided to have Dr Smithers look at it, and he decided to do prolotherapy. After a few treatments, the pain was completely gone. I’m thrilled to have found this clinic! And I highly recommend Dr Smithers!
Alex Smithers is not only smart and so helpful with my husband and his knee problems but he helped me with my stomach issues. I would go to him before I tried any other form of medicine. Thank you Alex!!
Thank you Dr. Alex Smithers! After dealing with lower back pain from an injury 30 years ago, I feel that after several injections, I am pain and worry free and can finally let this go.
I was back today for a torn knee ligament and the first ozone injection, and am confident this will be healed also.
Alex is unlike others in the medical field. He has a calm professional manner and very patient in listening and explaining... Read more »
Doctor Alex has been treating me for severe gut issues. I was tired of going to doctors that didn’t listen to me and would just prescribe a pill not ever trying to get to the real issues I was having. Dr. Alex has listened and treated me holistically and I am feeling great!! Thank you for everything Dr. Alex.
I was told i needed surgery and that i should file for social security disability… I thought my life was over . Thanks to Dr Smithers i didn’t have to do either.. I will be eternally grateful… I’m back at work and looking forward to a bright future..