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Name: Integral Medicine | Alexander Smithers M.D., A.P.
Telephone: 941-444-6336

FDA Grants RMAT Status to Allocetra, a Cell Therapy for Knee Osteoarthritis

By asmithers | Published July 14, 2026

FDA Grants RMAT Status to Allocetra, a Cell Therapy for Knee Osteoarthritis

The FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation to Allocetra, an investigational cell therapy from Enlivex, for age-related symptomatic knee osteoarthritis in adults 64 and older. The designation is based on six-month data showing durable improvements in pain and function.

What Happened

The FDA has granted Continue reading

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Beyond Mold: A Complete Guide to Biotoxin Illness (CIRS) and How to Recover

By asmithers | Published July 13, 2026

If you have spent months or years cycling through specialists, collecting vague diagnoses like fibromyalgia or chronic fatigue syndrome, and feeling as though your body has become a stranger to you, you are not alone. You may be dealing with Biotoxin Illness/CIRS, a condition Continue reading

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Medical Ozone Therapy for Chronic Fatigue: Energy Restoration

By asmithers | Published July 1, 2026

If you are living with chronic fatigue that rest cannot fix, you know the difference between being tired and being depleted. The exhaustion that defines myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is not the kind you can sleep off. It is a profound, cellular collapse that steals your ability Continue reading

Why You Keep Getting UTIs Even After Antibiotics — And What’s Really Going On

By asmithers | Published June 13, 2026

It can be incredibly frustrating to experience a urinary tract infection (UTI) that just won’t go away, especially after completing a course of antibiotics. You might wonder, “Why do I keep getting UTIs even after antibiotics?” This is a common concern, and understanding the underlying reasons is key to finding effective solutions. This article delves into the complexities of recurrent UTI Continue reading

Posted in What We Treat | Also tagged Chronic Interstitial Cystitis, Chronic UTI, Integrative Medicine Sarasota Fl, Natural UTI treatment, Naturall interstitial Cystitis Treatment, Prolotherapy Sarasota Fl, Prolozone Sarasota Fl Comments Off on Why You Keep Getting UTIs Even After Antibiotics — And What’s Really Going On

Mycotoxin Illness: Recognition and Management from Functional Medicine Perspective Alice Prescott Sullivan 1

By asmithers | Published July 21, 2025

Abstract

Mold toxin exposure by inhalation and ingestion has significant health consequences for humans. In this article, we discuss the sources of these everyday toxins and their relevance to patient health. The effects of mycotoxins can present across all body systems, and the resulting symptoms can be acute, cumulative, and chronic. These effects can occur discretely, but they can also Continue reading

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Integral Medicine | Alexander Smithers M.D., A.P.

1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336

1014 N. East Ave.
Sarasota, Fl. 34237

941-444-6336

Testimonials

In Oct of 2013 I was diagnosed with stage 4 Cholangiocarcinoma Malignant Neoplasm Cancer of the Bile Ducts of the Liver. In addition I had a tumor on the left lobe of the liver that ruptured and allowed cancer cells to escape and cake on the majority of my abdominal area. The issues, pain and effects are too numerous to mention. After 9 months of Chemo Therapy Treatments I was left with major issues with neuropathy in both my feet... Read more »
Thank you Dr. Alex Smithers! After dealing with lower back pain from an injury 30 years ago, I feel that after several injections, I am pain and worry free and can finally let this go.
I was back today for a torn knee ligament and the first ozone injection, and am confident this will be healed also.
Alex is unlike others in the medical field. He has a calm professional manner and very patient in listening and explaining... Read more »
Dr. Smithers has been taking care of my knees for a few years now. My experience with him has been consistently outstanding. His care has allowed me to avoid knee replacement surgery. There was a point when I had so much pain that I was not able to spend more than 15 minutes on my feet.. Because of his treatments and direction I have gotten my life back, including 20 mile bike rides and trips to the Disney parks with... Read more »

Testimonials

Dr Smithers is so acute and atuned to what others miss. I had been suffering with abdominal issues for over 20 years getting no help from traditional medicine. He found and correctly treated the issue. Words cannot describe the quality of life that has been restored to me. He’s very caring and takes the time to listen.
I became interested in pursuing ozone injections from Dr. Smithers after a friend received the treatments
and recommended it to me. I just finished my second round of injections in my neck, lower back, hips and both knees. I have experienced lower back/hip pain most of my adult life, endured a knee injury while white river rafting in my 20’s and have had progressively worsening neck pain since a car wreck in my early 30’s. For reference I am 47... Read more »
Dr. Alex Smithers is outstanding…a talented Dr. Who is extremely passionate about healing as well as the skills involved in rejuvenative therapies. I go to him for ozone (prolozone) and dextrose (prolotherapy) injections. Have gone to him already at least 8 times. He uses ultrasound to diagnose and monitor and his injections really work. Best of all he’s a great guy and very easy to chat with.
I had been suffering from chronic neck and shoulder pain for almost 2 decades. I tried chiropractic and acupuncture, which didn’t do anything for my pain. Using essential oils and CBD would help, but that was a temporary fix. Through an online documentary, I found this clinic in Sarasota. Meeting Dr. Smithers was the best thing that ever happened to me. He’s not just a very competent doctor, he’s also very compassionate and patient. He’s extremely knowledgeable and well read,... Read more »
Thank you Dr. Alex Smithers! After dealing with lower back pain from an injury 30 years ago, I feel that after several injections, I am pain and worry free and can finally let this go.
I was back today for a torn knee ligament and the first ozone injection, and am confident this will be healed also.
Alex is unlike others in the medical field. He has a calm professional manner and very patient in listening and explaining... Read more »
I was told i needed surgery and that i should file for social security disability… I thought my life was over . Thanks to Dr Smithers i didn’t have to do either.. I will be eternally grateful… I’m back at work and looking forward to a bright future..